USA Directory > Science > Biology

  • ADC characterization
    Pharmacokinetics (PK) studies provide critical information regarding the behavior of a drug in circulation and its ultimate form after extensive in vivo metabolism.
    US www.creative-biolabs.com/adc/adc-pharmacokinetics-characterization.htm
  • lentiviral vector
    Aiming at genetically modifying T cells with designed CAR, our scientists flexibly adopt versatile methodologies to transfect CAR construction into T cells, such as packing and transfection with virus based transfection methods.
    US www.creative-biolabs.com/car-t/gene-packaging-delivery.htm
  • in vivo animal testing
    Taking advantage of the CellRapeutics™ platform, Creative Biolabs provides customized, standardized, reliable and high-quality CAR-T preclinical in vivo assay services for clients across the world.
    US www.creative-biolabs.com/car-t/car-t-preclinical-in-vivo-assay.htm
  • Car design development
    In detail, CAR stands for chimeric antigen receptor or artificial T cell receptor, which is engineered elaborately and endowing an immune effector cell (T cell) with an arbitrary specificity via a monoclonal antibody.
    US www.creative-biolabs.com/car-t/car-design-construction.htm
  • Car t cell evaluation
    At Creative Biolabs, our scientists will professionally perform multiple evaluations on the post-transfection CAR-T cells to verify the solid success of CAR-T construction and superior function. With advanced technologies and experienced researchers.
    US www.creative-biolabs.com/car-t/car-cell-in-vitro-assay-service.htm
  • Car t biomarker
    In a narrow sense of cancer biomarker, it is limited to proteins the most used to challenge in the clinical applications, especially in the CAR-T therapy.
    US www.creative-biolabs.com/car-t/biomarker-identification-selection.htm
  • CD19
    Currently, anti-CD19 CAR-T cell therapies for B-cell malignancies are the most advanced engineered T cell therapies being tested. Clinical trials in ALL and CLL have exhibited robust and striking clinical efficacy.
    US www.creative-biolabs.com/car-t/anti-cd19-car-t-preclinical-in-vivo-assay.htm
  • Vaccination
    Vaccine technology has evolved significantly in the last decade. To accelerate response time to emerging threats, develop vaccines against difficult targets, Creative Biolabs offers a full range of vaccine design and production services.
    US www.creative-biolabs.com/vaccine/
  • Auristatin
    Auristatins are a family of complex analogues to the native antineoplastic product dolastatin 10. They are 100 to 1000 times more toxic than Doxorubicin, a conventional cancer chemotherapy medication.
    US www.creative-biolabs.com/adc/auristatins.htm
  • Cysteine conjugation
    As an industrial leader in antibody-drug conjugate (ADC) development and with our experienced science teams, Creative Biolabs provides the most comprehensive cysteine-based conjugation approaches to generate highly customized ADCs in a timely.
    US www.creative-biolabs.com/adc/cysteine-based-conjugation.htm
  • ADC payload
    Antibody-drug conjugates (ADCs) are next-generation targeted anti-tumor agents that are constructed by the covalent coupling of a monoclonal antibody with a cytotoxic payload drug via a small molecular linker. As a key factor in an ADC, the payload d
    US www.creative-biolabs.com/adc/drug-module.htm
  • Duocarmycin ADC
    Duocarmycins are a series of natural products originally isolated from Streptomyces bacteria in 1988. They exhibit an impressively high cytotoxicity and are subsequently developed into anti-tumor agents.
    US www.creative-biolabs.com/adc/duocarmycins.htm
  • ipatasertib
    Ipatasertib, also known as GDC-0068, is a strong ATP-competitive pan-AKT inhibitor. It was initially derived during the screening and optimization process of a series of 6,7-dihydro-5H-cyclopenta[d]pyrimidine compounds.
    US www.creative-biolabs.com/adc/ipatasertib-akt-inhibitor.htm
  • ADC platform
    ADCs are next-generation precision medicines that target specific surface antigens and fight diseases by delivering cytotoxic payload drugs into the antigen-bearing cells. ADCs are trending in immunotherapy and are believed to have high potential and
    US www.creative-biolabs.com/adc/platform.htm
  • ph sensitive linker
    pH-sensitive linkers (acid-labile linkers), are a class of chemically cleavable linkers that were first used in early ADC developments. Hydrazonesand cis-Aconityl is among the most widely used pH-sensitive linkers. A cis-aconityl linkage is offen use
    US www.creative-biolabs.com/adc/ph-sensitive-linker.htm
  • Ceavable linker
    Linker design for ADCs is highly dependent on the biolology of the target cells, the characteristics of the antibody, and the structure of the drug molecule. Selection of the optimal linker is achieved through efficacy and toxicity assessments for ea
    US www.creative-biolabs.com/adc/linker-module.htm
  • Acetyl Tetrapeptide-5
    Acetyl tetrapeptisde-5 is a known humectant or hydroscopic moisturizer which helps reduce eye puffiness, improve skin elasticity and overall smoothness.
    US www.creative-peptides.com/product/acetyl-tetrapeptide-item-cpc1610-134.html
  • FRET-Substrates
    Creative Peptides provides a wide range of fret substrates.
    US www.creative-peptides.com/product/fret-substrates-35.html
  • Fibroblast Cells
    Fibroblasts, the most common mammalian connective tissue cells, are specialized for the secretion of collagenous extracellular matrix and are jointly responsible for the architectural framework of the body. A fibroblast cell plays a critical role in
    US www.creative-bioarray.com/filter/fibroblast-cell-and-media-12.html
  • Mouse lung fibroblasts
    Mouse Primary Lung Fibroblasts are isolated from tissue of pathogen-free laboratory mice. Mouse Primary Lung Fibroblasts are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Creative Bioarray Cul
    US www.creative-bioarray.com/mouse-lung-fibroblasts-CSC-C1937-item-39372.htm